Caplacizumab
Cablivi (caplacizumab) is a monoclonal antibody fragment used to treat acquired thrombotic thrombocytopenic purpura (aTTP), a rare blood disorder. It works by inhibiting platelet aggregation and is administered as a subcutaneous injection alongside plasma exchange and immunosuppression therapy.
Cablivi is a specialized medication for treating acquired thrombotic thrombocytopenic purpura by preventing blood clots from forming.
Key facts at a glance
- RxNorm
- 2110610
- Generic
- Cablivi
- Class
- brand-name
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Cablivi is indicated for the treatment of acquired thrombotic thrombocytopenic purpura (aTTP) in adults, typically used in combination with plasma exchange and immunosuppressive therapy.
Cablivi is a von Willebrand factor (vWF) directed antibody fragment that inhibits the interaction between vWF and platelets, thereby preventing the formation of microthrombi characteristic of aTTP.
Common side effects may include bleeding and injection site reactions. Patients should be monitored for signs of bleeding, particularly those undergoing surgery or invasive procedures. This medication does not replace standard therapies but is used as an adjunct treatment.
Official drug label
WellAlly may earn a referral fee from linked resources at no extra cost to you. Editorial content is never influenced by commercial relationships.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed September 3, 2026. · Read our editorial policy