Cafedrine / Theodrenaline
Cafedrine/Theodrenaline is a combination medication that acts as a circulatory stimulant, combining a caffeine derivative with a sympathomimetic agent. It is primarily used to treat low blood pressure (hypotension) and circulatory insufficiency, particularly in surgical or perioperative settings. The medication works by stimulating both alpha and beta adrenergic receptors to increase vascular tone and cardiac output.
A circulatory stimulant combination medication used to raise blood pressure in cases of hypotension or circulatory insufficiency.
Key facts at a glance
- RxNorm
- 17214
- Generic
- Cafedrine / Theodrenaline
- Class
- multi-ingredient
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Treatment and prevention of hypotension during surgical procedures (particularly spinal/epidural anesthesia), management of circulatory insufficiency, and orthostatic hypotension. May also be used in intensive care settings for blood pressure support.
Combines cafedrine (a caffeine-related compound with central stimulating properties) with theodrenaline (a sympathomimetic amine with alpha and beta adrenergic activity). Together they increase vascular resistance and cardiac output, raising blood pressure through vasoconstriction and enhanced heart function.
Administered by injection in clinical settings where cardiac monitoring is available. Contraindicated in patients with cardiovascular disease, uncontrolled hypertension, or hyperthyroidism. Common side effects include tachycardia, palpitations, headache, and nausea. Use requires careful dosing and monitoring, particularly in elderly patients or those with underlying cardiac conditions.
Official drug label
WellAlly may earn a referral fee from linked resources at no extra cost to you. Editorial content is never influenced by commercial relationships.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 28, 2026. · Read our editorial policy