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Caffeine / Dimenhydrinate

Published: July 27, 2026Updated: August 28, 2026

This combination medication pairs dimenhydrinate, an antihistamine that helps relieve nausea and vertigo, with caffeine to counteract drowsiness. It is primarily used to treat and prevent symptoms associated with motion sickness and vestibular disorders. The caffeine component helps patients remain alert while managing their symptoms.

Quick summary

A combination of an antihistamine and stimulant used to prevent motion sickness and treat vertigo while reducing drowsiness.

Medically reviewed by WellAlly Editorial TeamLast reviewed August 28, 2026Editorial policy

Key facts at a glance

RxNorm
1008947
Generic
Caffeine / Dimenhydrinate
Class
multi-ingredient
Brands
—
Availability
rx
Lactation
unknown
Routes
—
Forms
—
Regions
US, EU, CN, JP
Monitoring
—

This page is for informational purposes only.

Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.

Prevention and treatment of motion sickness, vertigo, and associated symptoms such as nausea, vomiting, and dizziness. May also be used for dizziness related to inner ear disorders.

Dimenhydrinate blocks histamine receptors and reduces activity in the vomiting center of the brain, while caffeine acts as a mild stimulant to offset the sedating effects of the antihistamine component.

May cause drowsiness; avoid operating machinery or driving until you know how this medication affects you. Avoid alcohol and other central nervous system depressants. Consult a healthcare provider before use if pregnant, breastfeeding, or taking other medications. Not recommended for prolonged use without medical supervision.

Official drug label

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Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 28, 2026. · Read our editorial policy