Caffeine / Magnesium Salicylate
Caffeine/Magnesium Salicylate is a combination analgesic medication used for temporary relief of minor aches, pains, and headaches. The magnesium salicylate component provides anti-inflammatory and pain-relieving effects, while caffeine may enhance these effects and help constrict dilated blood vessels associated with certain headaches.
A combination pain reliever containing a salicylate and caffeine, used for minor aches, pains, and headaches.
Key facts at a glance
- RxNorm
- 1001434
- Generic
- Caffeine / Magnesium Salicylate
- Class
- multi-ingredient
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Temporary relief of minor aches and pains associated with headaches, muscle aches, backaches, menstrual cramps, minor arthritis pain, and common cold. May also be used for tension headaches.
Magnesium salicylate works by inhibiting cyclooxygenase (COX) enzymes, reducing prostaglandin production to decrease pain, inflammation, and fever. Caffeine is added as an analgesic adjuvant—it may enhance pain relief, particularly for headaches, through vasoconstriction of dilated cerebral blood vessels and adenosine receptor antagonism.
Not for use in individuals allergic to aspirin or salicylates. Avoid use in children/teens recovering from viral infections (Reye's syndrome risk). Use cautiously in those with bleeding disorders, kidney problems, or gastrointestinal issues. Should not be combined with blood thinners or other NSAIDs without medical supervision. Consult a healthcare provider before use if pregnant, breastfeeding, or taking other medications.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 28, 2026. · Read our editorial policy