Caffeine / Phenacetin / Salicylamide / Styramate
This combination medication contains an analgesic mixture (phenacetin and salicylamide) enhanced with caffeine for increased effectiveness, along with a muscle relaxant component (styramate). It is primarily used to treat tension headaches, muscle pain, and mild to moderate pain conditions where both pain relief and muscle relaxation are desired.
A combination analgesic with muscle relaxant properties used for tension-related pain and headaches.
Key facts at a glance
- RxNorm
- 690832
- Generic
- Caffeine / Phenacetin / Salicylamide / Styramate
- Class
- multi-ingredient
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Tension headaches, muscle pain, and mild to moderate pain conditions requiring both analgesic and muscle relaxant effects. May also be used for headache associated with sinus pressure or general aches.
Combines multiple analgesic compounds (phenacetin and salicylamide) with caffeine, which enhances pain relief, and styramate, a muscle relaxant that helps relieve tension in skeletal muscles. The multi-ingredient approach targets pain through several pathways simultaneously.
Should not be used by individuals with kidney problems (due to phenacetin content), those with bleeding disorders, or during pregnancy without medical supervision. Caffeine content may cause insomnia, jitters, or interact with other stimulants. Avoid alcohol during treatment. Not recommended for long-term continuous use due to potential kidney toxicity from phenacetin.
Official drug label
WellAlly may earn a referral fee from linked resources at no extra cost to you. Editorial content is never influenced by commercial relationships.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 28, 2026. · Read our editorial policy