Calamine / Dimethicone / Zinc Oxide
This is a topical skin protectant medication combining calamine, dimethicone, and zinc oxide to soothe irritated skin and provide a protective barrier. It is commonly used to treat diaper rash in infants and relieve minor skin irritations such as dryness, itching, and redness in both children and adults.
A topical skin protectant used to soothe and protect irritated skin, commonly for diaper rash and minor skin irritations.
Key facts at a glance
- RxNorm
- 1007289
- Generic
- Calamine / Dimethicone / Zinc Oxide
- Class
- multi-ingredient
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Treatment and prevention of diaper rash, relief of minor skin irritations, dry or itchy skin, sunburn, and skin conditions causing discomfort and redness.
The combination creates a protective barrier on the skin surface. Zinc oxide and calamine soothe irritation and reduce inflammation, while dimethicone seals in moisture and protects against external irritants and friction.
For external use only. Avoid contact with eyes. Discontinue use and consult a healthcare provider if irritation worsens or does not improve. Keep out of reach of children. Do not use on deep or infected wounds.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 28, 2026. · Read our editorial policy