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Calamine / Menthol / Zinc Oxide

Published: July 27, 2026Updated: August 28, 2026

This medication is a topical combination product containing calamine, menthol, and zinc oxide that provides relief from itching, irritation, and minor skin discomfort. It is commonly used for conditions like poison ivy, insect bites, sunburn, and heat rash. The combination works by soothing the skin while also providing a cooling sensation and protective barrier.

Quick summary

A topical anti-itch medication used to relieve minor skin irritations from causes like poison ivy, insect bites, and sunburn.

Medically reviewed by WellAlly Editorial TeamLast reviewed August 28, 2026Editorial policy

Key facts at a glance

RxNorm
1373248
Generic
Calamine / Menthol / Zinc Oxide
Class
multi-ingredient
Brands
Lantiseptic Multi-Purpose
Availability
rx
Lactation
unknown
Routes
—
Forms
—
Regions
US, EU, CN, JP
Monitoring
—

This page is for informational purposes only.

Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.

Used to relieve itching, irritation, and discomfort from poison ivy, poison oak, insect bites, sunburn, heat rash, chickenpox, and other minor skin irritations.

Calamine and zinc oxide provide soothing and protective properties that help calm irritated skin, while menthol creates a cooling sensation that distracts from itching and provides a refreshing feeling.

For external use only. Avoid contact with eyes and mucous membranes. Do not apply to broken or blistered skin unless directed by a healthcare provider. Shake well before use if using a liquid formulation. Discontinue use and consult a doctor if irritation worsens.

Official drug label

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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 28, 2026. · Read our editorial policy