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Calamine / Phenol

Published: July 27, 2026Updated: August 28, 2026

Calamine/Phenol is a topical combination medication used to relieve itching, irritation, and minor skin discomfort. It is commonly applied to conditions such as sunburn, poison ivy, insect bites, and other superficial skin irritations. The mixture combines the soothing properties of calamine with the mild antiseptic and anesthetic effects of phenol.

Quick summary

A topical skin medication that relieves itching and minor skin irritations through combined soothing and antiseptic action.

Medically reviewed by WellAlly Editorial TeamLast reviewed August 28, 2026Editorial policy

Key facts at a glance

RxNorm
215815
Generic
Calamine / Phenol
Class
multi-ingredient
Brands
—
Availability
rx
Lactation
unknown
Routes
—
Forms
—
Regions
US, EU, CN, JP
Monitoring
—

This page is for informational purposes only.

Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.

This medication is used to treat minor skin itching and irritation from sources such as sunburn, poison ivy/oak/sumac, insect bites, chickenpox, and other transient skin conditions causing discomfort.

Calamine provides a cooling, protective barrier that soothes irritated skin, while phenol acts as a mild antiseptic and topical anesthetic to reduce discomfort and prevent infection in minor skin abrasions.

For external use only; avoid contact with eyes and mucous membranes. Do not apply to large areas of broken skin or use on deep wounds. Discontinue use if irritation, burning, or rash worsens. Consult a healthcare provider if symptoms persist beyond 7 days or for use on children under 2 years of age.

Official drug label

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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 28, 2026. · Read our editorial policy