Calamine / Pramoxine / Zinc Oxide
This combination topical medication provides temporary relief from itching, pain, and irritation caused by minor skin conditions such as rashes, insect bites, poison ivy, and sunburn. It is applied directly to the skin and combines protective, anesthetic, and anti-itch properties to soothe irritated skin.
A topical combination product that relieves itching, pain, and irritation from minor skin conditions like rashes, bites, and sunburn.
Key facts at a glance
- RxNorm
- 1798480
- Generic
- Calamine / Pramoxine / Zinc Oxide
- Class
- multi-ingredient
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Used to relieve itching, pain, and irritation associated with minor skin conditions including poison ivy, poison oak, poison sumac, insect bites, sunburn, minor burns, and other rashes.
Calamine and zinc oxide create a protective barrier on the skin with mild astringent properties, while pramoxine provides local anesthetic relief by temporarily numbing the skin to reduce itching and discomfort.
For external use only. Avoid contact with eyes, nose, and mouth. Do not apply to deep or infected wounds. Discontinue use if irritation worsens or if rash persists beyond 7 days without improvement.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 28, 2026. · Read our editorial policy