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Calamine / Resorcinol / Sulfur, Colloidal

Published: July 27, 2026Updated: August 28, 2026

This is a topical combination medication containing calamine, resorcinol, and colloidal sulfur, commonly used to treat various skin conditions including acne, eczema, and psoriasis. The three ingredients work together as a keratolytic and antiseptic preparation—calmine soothes irritated skin, resorcinol helps break down dead skin cells, and colloidal sulfur provides antibacterial and antifungal properties. It is typically applied directly to affected skin areas as directed by a healthcare provider.

Quick summary

A topical multi-ingredient skin medication used to treat acne and other inflammatory skin conditions through its combined antiseptic, keratolytic, and soothing effects.

Medically reviewed by WellAlly Editorial TeamLast reviewed August 28, 2026Editorial policy

Key facts at a glance

RxNorm
1007875
Generic
Calamine / Resorcinol / Sulfur, Colloidal
Class
multi-ingredient
Brands
—
Availability
rx
Lactation
unknown
Routes
—
Forms
—
Regions
US, EU, CN, JP
Monitoring
—

This page is for informational purposes only.

Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.

Used to treat acne vulgaris, eczema, psoriasis, seborrheic dermatitis, and other skin conditions involving inflammation, bacterial overgrowth, or excessive skin cell buildup.

Calamine provides soothing and astringent effects; resorcinol acts as a keratolytic agent to soften and shed dead skin cells; colloidal sulfur has antibacterial and antifungal properties that help reduce skin bacteria and control microbial overgrowth.

For external use only; avoid contact with eyes, mouth, and mucous membranes. May cause skin dryness, irritation, or photosensitivity. Resorcinol may cause temporary skin discoloration. Not recommended for use during pregnancy without medical advice. Sulfur has a distinct odor that some patients may find unpleasant.

Official drug label

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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 28, 2026. · Read our editorial policy