Calamine / Zinc Oxide
Calamine and Zinc Oxide is a topical over-the-counter medication commonly used to soothe minor skin irritations, itching, and rashes. It works as a skin protectant and astringent, forming a protective barrier on the skin while helping to absorb excess moisture and reduce inflammation. This medication is frequently used for conditions such as sunburn, poison ivy, chickenpox itching, eczema, and general skin irritation.
Topical skin protectant that soothes itching and minor skin irritations by forming a protective barrier on the skin.
Key facts at a glance
- RxNorm
- 645045
- Generic
- Calamine / Zinc Oxide
- Class
- multi-ingredient
- Brands
- Baby Anti Monkey Butt Diaper Rash Cream
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Used to relieve itching, redness, and irritation from minor skin conditions including sunburn, poison ivy/oak/sumac, chickenpox, eczema, insect bites, and general skin rashes. Also used as a protective barrier for minor wounds and diaper rash.
Forms a protective layer on the skin that helps seal out irritants and moisture. Has mild astringent properties that help dry out oozing and weeping skin lesions. Provides a cooling sensation that helps relieve itching and discomfort.
For external use only. Avoid contact with eyes and mucous membranes. Do not use on deep wounds or serious burns. Discontinue use and consult a healthcare provider if irritation worsens or persists. Keep out of reach of children.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 28, 2026. · Read our editorial policy