Calcium Carbonate / Cholecalciferol
Calcium Carbonate/Cholecalciferol is a combination supplement that provides elemental calcium along with Vitamin D3 to support bone health and treat or prevent calcium deficiency. This medication is commonly prescribed for patients at risk of osteoporosis, those with vitamin D deficiency, and individuals who have difficulty meeting their calcium needs through diet alone. The addition of Vitamin D3 enhances the absorption and utilization of calcium in the body.
A calcium and Vitamin D3 combination supplement used to support bone health and treat calcium deficiency.
Key facts at a glance
- RxNorm
- 608343
- Generic
- Calcium Carbonate / Cholecalciferol
- Class
- multi-ingredient
- Brands
- Oysco 500 with D, Os-Cal 500 with D, Cal-Quick, Caltrate Plus D, Ostercal-D, Oysco D, Osteo-Poretical
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Treatment and prevention of calcium deficiency and osteomalacia; management and prevention of osteoporosis; supplementation for individuals with inadequate dietary calcium or vitamin D intake, particularly elderly patients, postmenopausal women, and those with malabsorption disorders.
Calcium carbonate provides elemental calcium, an essential mineral for bone structure, muscle function, and nerve transmission. Cholecalciferol (Vitamin D3) is converted to its active form in the body to enhance intestinal absorption of calcium and maintain normal serum calcium and phosphate levels, supporting bone mineralization.
Take with food for optimal absorption; separate doses of this supplement from other medications by at least 2 hours (particularly tetracyclines, fluoroquinolones, and bisphosphonates). Monitor for signs of hypercalcemia (nausea, confusion, weakness) with prolonged high-dose use. Patients with kidney disease, hypercalcemia, or certain granulomatous diseases should use with caution under medical supervision.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 28, 2026. · Read our editorial policy