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Calcium Carbonate / Magnesium Hydroxide / Simethicone

Published: July 27, 2026Updated: August 28, 2026

This combination medication is an antacid and antiflatulent used to relieve symptoms of excess stomach acid and gas. It contains two antacids (calcium carbonate and magnesium hydroxide) that work by neutralizing stomach acid, while simethicone helps break up gas bubbles to reduce bloating and discomfort. This medication is typically used for conditions like heartburn, acid indigestion, and gas.

Quick summary

An over-the-counter antacid with antiflatulent properties that relieves heartburn, acid indigestion, and gas by neutralizing stomach acid and dispersing gas bubbles.

Medically reviewed by WellAlly Editorial TeamLast reviewed August 28, 2026Editorial policy

Key facts at a glance

RxNorm
691015
Generic
Calcium Carbonate / Magnesium Hydroxide / Simethicone
Class
multi-ingredient
Brands
—
Availability
rx
Lactation
unknown
Routes
—
Forms
—
Regions
US, EU, CN, JP
Monitoring
—

This page is for informational purposes only.

Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.

Treats heartburn, acid indigestion, sour stomach, gas, bloating, and pressure/discomfort caused by excess gas in the stomach and intestines.

Calcium carbonate and magnesium hydroxide neutralize excess stomach acid through chemical reactions, raising pH to reduce acidity and associated discomfort. Simethicone is a surface-active agent that changes the surface tension of gas bubbles, allowing them to combine and be more easily expelled or absorbed.

May interact with other medications; take at least 2 hours apart from other drugs. Those with kidney disease should use caution due to calcium and magnesium content. Not recommended for prolonged daily use without medical supervision. May cause constipation (calcium) or diarrhea (magnesium); effects often balance each other in combination products. Chew tablets thoroughly before swallowing.

Official drug label

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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 28, 2026. · Read our editorial policy