Calcium Sulfate Hemihydrate
Calcium Sulfate, Hemihydrate is a calcium salt commonly used in pharmaceutical manufacturing as an excipient in tablet formulations, and has applications in orthopedic surgery as a bone void filler. This pin-variant formulation is primarily utilized for its binding and setting properties in solid dosage forms.
Calcium Sulfate, Hemihydrate serves as a pharmaceutical excipient and bone graft material with calcium supplementation properties.
Key facts at a glance
- RxNorm
- 1310466
- Generic
- Calcium Sulfate, Hemihydrate
- Class
- pin-variant
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Used in pharmaceutical tablet formulations as a binder and diluent, in orthopedic procedures as a bone void filler or graft substitute, and may serve as a calcium source in dietary supplement formulations.
When hydrated, calcium sulfate hemihydrate converts to the dihydrate form and hardens, providing structural support. As a calcium source, it contributes elemental calcium for bone mineralization and physiological functions.
Drug class is listed as pin-variant. Use as a bone graft material should be performed by qualified healthcare professionals. Contraindicated in patients with hypercalcemia or severe renal impairment. Drug interactions may occur with tetracycline antibiotics and other calcium-affecting medications.
Official drug label
WellAlly may earn a referral fee from linked resources at no extra cost to you. Editorial content is never influenced by commercial relationships.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 25, 2026. · Read our editorial policy