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Carbetapentane

Published: July 26, 2026Updated: August 24, 2026

Carbetapentane is a non-opioid cough suppressant (antitussive) used to temporarily relieve coughing associated with upper respiratory conditions such as colds, allergies, or bronchitis. It works by suppressing the cough reflex in the brain to reduce the urge to cough.

Quick summary

Carbetapentane is a non-opioid antitussive medication used to relieve cough symptoms.

Medically reviewed by WellAlly Editorial TeamLast reviewed August 24, 2026Editorial policy

Key facts at a glance

ATC
R05DB05
RxNorm
20217
Generic
Carbetapentane
Class
atc-r05
Brands
Tannic-12 S, Allfen CX
Availability
rx
Lactation
unknown
Routes
oral
Forms
tablet, solution, suspension
Regions
US, EU, CN, JP
Monitoring
—

This page is for informational purposes only.

Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.

Dosage and administration

adult (standard)tablet
Usual dose
10-12.5mg twice daily
Maximum
consult physician
Frequency
every 12 hours
Instructions
Follow physician instructions
Duration limits
as prescribed
Monitoring
standard
pediatric (standard)tablet
Usual dose
5-6.25mg twice daily
Maximum
consult physician
Frequency
every 12 hours
Instructions
Follow physician instructions
Duration limits
as prescribed
Monitoring
standard
geriatric (standard)tablet
Usual dose
10mg once or twice daily
Maximum
consult physician
Frequency
every 12 hours as needed
Instructions
Follow physician instructions
Duration limits
as prescribed
Monitoring
standard

Overdose information

Important overdose information
Toxic dose: Specific toxic dose not well established; toxicity may vary based on individual factors
Chronic overdose: Prolonged use exceeding recommended doses may lead to cumulative toxicity
Immediate actions
supportive care, airway management, activated charcoal if within 1 hour of ingestion
Antidote
naloxone(effective for reversing respiratory depression if opioid-mediated toxicity)
Poison Control: 1-800-222-1222

Special Populations

8 groups
✗

pregnancy

first trimester
unsafe
FDA Category
C
Dose Adjustment

avoid if possible

Key Recommendations

avoid use during pregnancy unless benefits outweigh risks

Monitor

regular fetal monitoring

Use of this medication in this population requires careful consideration of risks and benefits.

⚠

pregnancy

second third trimester
caution
FDA Category
C
Dose Adjustment

use lowest effective dose

Key Recommendations

use only if clearly needed and benefits outweigh risks

Monitor

fetal monitoring as needed

Use with caution and monitor for adverse effects.

?

lactation

breastfeeding
unknown
FDA Category
N
Dose Adjustment

avoid or discontinue breastfeeding

Key Recommendations

decide whether to discontinue breastfeeding or discontinue drug

Monitor

monitor infant for sedation or breathing changes

✗

pediatric_age

under 2 years
contraindicated
FDA Category
C
Dose Adjustment

do not use

Key Recommendations

not recommended in children under 2 years

Monitor

n/a

Use of this medication in this population requires careful consideration of risks and benefits.

⚠

pediatric_age

2 12 years
caution
FDA Category
C
Dose Adjustment

weight-based dosing required

Key Recommendations

use with caution only under healthcare provider supervision

Monitor

monitor for sedation and respiratory depression

Use with caution and monitor for adverse effects.

⚠

geriatric

elderly
caution
FDA Category
C
Dose Adjustment

start with lower dose

Key Recommendations

use with caution due to increased sensitivity to CNS effects

Monitor

monitor for dizziness and sedation

Use with caution and monitor for adverse effects.

⚠

renal_impairment

mild moderate
caution
FDA Category
C
Dose Adjustment

no adjustment needed for mild to moderate

Key Recommendations

use with caution

Monitor

monitor renal function periodically

Use with caution and monitor for adverse effects.

⚠

hepatic_impairment

mild moderate
caution
FDA Category
C
Dose Adjustment

no specific adjustment for mild to moderate

Key Recommendations

use with caution

Monitor

monitor liver function

Use with caution and monitor for adverse effects.

Statistics and clinical data

prescribingFDA
2023

Commonly prescribed since

Value:1950s

General prescribing information

drug_classWHO
2023

Drug class

Value:Antitussive (Cough Suppressant)

Drug class information

usageMedical guidelines
2023

Common uses

Value:Cough suppression, Upper respiratory tract infections

Common therapeutic uses

mechanismPharmacology references
2023

Mechanism of action

Value:Suppresses cough reflex by acting on central nervous system

Pharmacological action

Temporary relief of cough associated with the common cold, allergies, bronchitis, sinusitis, or other upper respiratory tract conditions. Often found in combination products with other cold symptom relievers.

As an antitussive agent, it suppresses the cough reflex in the central nervous system. It has both antitussive and mild anticholinergic properties that help reduce excessive coughing.

Available by prescription only in many regions. Should not be used for persistent coughs due to conditions like asthma, emphysema, or smoking. May cause drowsiness in some patients. Consult a healthcare provider before use if pregnant, breastfeeding, or taking other medications.

Contraindications

Conditions and patient states where this medication should be avoided or used with caution.

Do not use (1)

ABSOLUTEhypersensitivity

Known allergy to this medication or its components

Use caution (1)

RELATIVEpregnancy

Consult healthcare provider for benefits vs risks assessment

Official drug label

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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 24, 2026. · Read our editorial policy