Carbinoxamine
Carbinoxamine is an antihistamine medication used to treat symptoms of allergic reactions, including runny nose, sneezing, itchy or watery eyes, and skin rashes. It works by blocking histamine H1 receptors, reducing allergic responses throughout the body. This medication is available by prescription and is typically used in both children and adults.
Carbinoxamine is a prescription antihistamine that relieves allergy symptoms by blocking histamine receptors.
Key facts at a glance
- ATC
- R06AA08
- RxNorm
- 20220
- Generic
- Carbinoxamine
- Class
- atc-r06
- Brands
- Karbinal, Ryvent, Carbzah
- Availability
- rx
- Lactation
- unknown
- Routes
- oral
- Forms
- suspension, solution, tablet
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Dosage and administration
- Usual dose
- 4mg every 12 hours
- Maximum
- consult physician
- Frequency
- every 12 hours
- Instructions
- Follow physician instructions
- Duration limits
- as prescribed
- Monitoring
- standard
- Usual dose
- 2mg every 12 hours
- Maximum
- consult physician
- Frequency
- every 12 hours
- Instructions
- Follow physician instructions
- Duration limits
- as prescribed
- Monitoring
- standard
- Usual dose
- 4mg every 12 hours
- Maximum
- consult physician
- Frequency
- every 12 hours
- Instructions
- Follow physician instructions
- Duration limits
- as prescribed
- Monitoring
- standard
Overdose information
Special Populations
11 groupspregnancy
first trimesteravoid if possible
avoid use during pregnancy unless benefits outweigh risks
regular fetal monitoring
Use of this medication in this population requires careful consideration of risks and benefits.
pregnancy
second trimesterreduce dose if needed
use only if clearly needed and benefits outweigh risks
monitor for uterine activity and fetal well-being
Use with caution and monitor for adverse effects.
pregnancy
third trimesterreduce dose and avoid near delivery
avoid use close to delivery, may cause fetal distress
monitor for neonatal respiratory depression and sedation
Use with caution and monitor for adverse effects.
lactation
not applicableavoid
avoid breastfeeding during treatment and for 24 hours after last dose
monitor infant for sedation, irritability, and feeding difficulties
Use of this medication in this population requires careful consideration of risks and benefits.
pediatric_age
under 2 yearsnot applicable
contraindicated in children under 2 years due to risk of serious adverse reactions including respiratory depression
not recommended
Use of this medication in this population requires careful consideration of risks and benefits.
pediatric_age
2 to 12 yearsweight-based dosing, do not exceed recommended limits
use with caution, avoid in children with asthma or lower respiratory conditions
monitor for sedation, anticholinergic effects, and respiratory changes
Use with caution and monitor for adverse effects.
geriatric
over 65 yearsstart with lowest effective dose, consider dose reduction
use with caution due to increased sensitivity to anticholinergic effects, avoid operating machinery
monitor for falls, confusion, urinary retention, and constipation
Use with caution and monitor for adverse effects.
renal_impairment
mildno major adjustment needed
use with caution, monitor renal function
monitor renal function periodically
Use with caution and monitor for adverse effects.
renal_impairment
severereduce dose by 25-50%
use with caution, consider extended dosing interval
frequent monitoring of renal function and drug levels if available
Use with caution and monitor for adverse effects.
hepatic_impairment
mild to moderatereduce dose by 25-50%
use with caution, metabolized in liver
monitor for increased sedation and anticholinergic effects
Use with caution and monitor for adverse effects.
hepatic_impairment
severeavoid or significantly reduce dose
avoid if possible due to severely impaired metabolism
close monitoring required if use is necessary
Use of this medication in this population requires careful consideration of risks and benefits.
Statistics and clinical data
Commonly prescribed since
First FDA approval date for Carbinoxamine formulations
Drug class
ATC Code R06AA06 - Antihistamines, plain
Common uses
FDA-approved therapeutic indications
Available formulations
Available dosage forms for Carbinoxamine (Karbinal, Ryvent, Carbzah)
Treatment of seasonal and perennial allergic rhinitis, vasomotor rhinitis, allergic conjunctivitis, and mild allergic skin reactions such as urticaria and angioedema
Carbinoxamine is an H1 antihistamine that competitively blocks histamine receptors in the GI tract, blood vessels, and respiratory system, preventing allergic symptoms. It also has anticholinergic effects that help reduce secretions and sedative properties.
May cause drowsiness; avoid alcohol and operating machinery until known. Use caution in elderly patients and those with glaucoma, urinary retention, or thyroid disorders. Not recommended for newborns or premature infants. May interact with MAO inhibitors and other CNS depressants.
Contraindications
Conditions and patient states where this medication should be avoided or used with caution.
Do not use (1)
Known allergy to this medication or its components
Use caution (1)
Consult healthcare provider for benefits vs risks assessment
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed July 26, 2026. · Read our editorial policy