Carboprost Tromethamine
Carboprost Tromethamine is a synthetic prostaglandin F2α analogue used primarily to control postpartum hemorrhage when conventional methods fail, and to terminate pregnancy in the second trimester. It works by stimulating uterine smooth muscle contraction and vasoconstriction to reduce bleeding. This medication is administered intramuscularly in healthcare settings with close medical supervision.
Carboprost is a uterotonic agent used to manage severe postpartum bleeding and second-trimester pregnancy termination through induced uterine contractions.
Key facts at a glance
- RxNorm
- 20259
- Generic
- Carboprost Tromethamine
- Class
- pin-variant
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Primarily used for refractory postpartum hemorrhage unresponsive to conventional treatments, and for termination of pregnancy in the second trimester, including management of incomplete or inevitable abortion.
Acts as a prostaglandin F2α receptor agonist, stimulating uterine smooth muscle contraction and promoting vasoconstriction to reduce uterine bleeding.
Contraindicated in patients with active asthma or known prostaglandin hypersensitivity. Common side effects include fever, chills, nausea, vomiting, diarrhea, and flushing. Requires administration in a healthcare setting with immediate access to resuscitation equipment. Use with caution in patients with cardiovascular disease, hypertension, or renal impairment.
Official drug label
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This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 27, 2026. · Read our editorial policy