Spironolactone
Cardalis is a veterinary medication for dogs containing a combination of benazepril (an ACE inhibitor) and spironolactone (a mineralocorticoid receptor antagonist). It is specifically formulated to manage congestive heart failure, particularly in dogs with myxomatous mitral valve disease (MMVD). This combination therapy helps reduce cardiac workload while protecting against harmful cardiac remodeling.
Cardalis is a prescription heart medication for dogs that combines two active ingredients to manage congestive heart failure and improve quality of life.
Key facts at a glance
- RxNorm
- 2566854
- Generic
- Cardalis
- Class
- brand-name
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Cardalis is indicated for the treatment of congestive heart failure in dogs, most commonly associated with myxomatous mitral valve disease (MMVD). It may be used when combined therapy with an ACE inhibitor and spironolactone is appropriate.
Benazepril is an ACE inhibitor that blocks the angiotensin-converting enzyme, reducing血管紧张素II levels and decreasing cardiac workload. Spironolactone is a potassium-sparing diuretic that acts as a mineralocorticoid receptor antagonist, providing additional cardioprotective effects by blocking harmful remodeling processes in the heart.
Cardalis is for veterinary use only in dogs. It should not be used in pregnant or lactating dogs. Regular monitoring of renal function and electrolyte levels is recommended during treatment. Side effects may include gastrointestinal upset, lethargy, or changes in appetite. Always use under veterinary supervision as part of a comprehensive heart disease management plan.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed July 26, 2026. · Read our editorial policy