Cariprazine Hydrochloride
Cariprazine Hydrochloride is an atypical antipsychotic medication used to treat schizophrenia, bipolar I disorder (manic, mixed, and depressive episodes), and major depressive disorder. It works by modulating dopamine and serotonin activity in the brain to help reduce symptoms of psychosis and mood disturbances.
An atypical antipsychotic used to treat schizophrenia and bipolar disorder by modulating dopamine and serotonin receptors.
Key facts at a glance
- RxNorm
- 1721073
- Generic
- Cariprazine Hydrochloride
- Class
- pin-variant
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
FDA-approved for treating schizophrenia in adults, acute manic or mixed episodes associated with bipolar I disorder, depressive episodes associated with bipolar I disorder, and major depressive disorder in adults.
Functions as a partial agonist at dopamine D2 and D3 receptors and serotonin 5-HT1A receptors, with particularly high affinity for D3 receptors. This partial agonism allows modulation of dopamine and serotonin activity in brain pathways involved in psychosis and mood regulation.
Common side effects include drowsiness, headache, nausea, and weight gain. May cause metabolic changes and extrapyramidal symptoms. Not recommended for elderly patients with dementia-related psychosis due to increased mortality risk. Requires regular monitoring and is typically taken once daily.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 27, 2026. · Read our editorial policy