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Carisoprodol

Published: July 26, 2026Updated: July 26, 2026

Carisoprodol is a muscle relaxant medication used to relieve discomfort associated with acute, painful musculoskeletal conditions such as strains, sprains, and other muscle injuries. It is typically prescribed for short-term use, usually 2-3 weeks, as the benefits are most apparent during acute phases of injury. The exact mechanism by which carisoprodol produces its muscle relaxant effects has not been fully established.

Quick summary

Carisoprodol is a short-term muscle relaxant used to treat acute musculoskeletal pain and discomfort.

Medically reviewed by WellAlly Editorial TeamLast reviewed July 26, 2026Editorial policy

Key facts at a glance

ATC
M03BA02
RxNorm
2101
Generic
Carisoprodol
Class
atc-m03
Brands
Soma, Vanadom
Availability
rx
Lactation
unknown
Routes
oral
Forms
tablet
Regions
US, EU, CN, JP
Monitoring
—

This page is for informational purposes only.

Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.

Dosage and administration

adult (standard)tablet
Usual dose
350mg three times daily and at bedtime
Maximum
consult physician
Frequency
every 6 hours as needed, not to exceed 1400mg daily
Instructions
Follow physician instructions
Duration limits
as prescribed
Monitoring
standard
pediatric (standard)tablet
Usual dose
Not recommended for patients under 16 years
Maximum
consult physician
Frequency
N/A
Instructions
Follow physician instructions
Duration limits
as prescribed
Monitoring
standard
geriatric (standard)tablet
Usual dose
350mg twice daily
Maximum
consult physician
Frequency
every 12 hours
Instructions
Follow physician instructions
Duration limits
as prescribed
Monitoring
standard

Overdose information

Important overdose information
Toxic dose: Doses exceeding 7-10 grams may result in severe CNS depression, respiratory failure, and potentially fatal outcomes
Chronic overdose: Prolonged use at supratherapeutic doses may lead to accumulation of carisoprodol and its metabolite meprobamate, causing persistent sedation, confusion, and physical dependence
Immediate actions
Secure airway and ensure adequate ventilation, administer activated charcoal if within 1-2 hours of ingestion, establish IV access, continuous cardiac monitoring
Antidote
No specific antidote exists(Treatment is supportive and symptomatic; early intervention improves outcomes significantly)
Poison Control: 1-800-222-1222

Special Populations

11 groups
⚠

pregnancy

first trimester
caution
FDA Category
C
Dose Adjustment

avoid if possible

Key Recommendations

use only if benefits outweigh risks; avoid during pregnancy unless absolutely necessary

Monitor

regular fetal monitoring recommended

Use with caution and monitor for adverse effects.

⚠

pregnancy

second trimester
caution
FDA Category
C
Dose Adjustment

use lowest effective dose

Key Recommendations

use only if benefits outweigh risks; avoid prolonged use

Monitor

regular prenatal checkups and fetal monitoring

Use with caution and monitor for adverse effects.

⚠

pregnancy

third trimester
caution
FDA Category
C
Dose Adjustment

avoid near term if possible

Key Recommendations

avoid use near delivery; may cause neonatal withdrawal symptoms

Monitor

monitor neonate for sedation and withdrawal signs after birth

Use with caution and monitor for adverse effects.

✗

lactation

breastfeeding
unsafe
FDA Category
N
Dose Adjustment

avoid or discontinue breastfeeding

Key Recommendations

carisoprodol is excreted in breast milk; avoid breastfeeding during treatment

Monitor

monitor infant for excessive drowsiness

Use of this medication in this population requires careful consideration of risks and benefits.

⚠

geriatric

elderly
caution
FDA Category
N
Dose Adjustment

reduce dose, start with 125mg

Key Recommendations

use with caution due to increased sensitivity; increased risk of falls and sedation

Monitor

monitor for sedation, dizziness, and balance issues

Use with caution and monitor for adverse effects.

✗

pediatric_age

children under 12
unsafe
FDA Category
N
Dose Adjustment

not recommended

Key Recommendations

not approved for use in pediatric patients under 12 years of age

Monitor

not applicable

Use of this medication in this population requires careful consideration of risks and benefits.

⚠

pediatric_age

adolescents 12 to 17
caution
FDA Category
N
Dose Adjustment

use with caution, weight-based dosing

Key Recommendations

use only if benefits outweigh risks; monitor for adverse effects

Monitor

monitor for sedation and CNS depression

Use with caution and monitor for adverse effects.

⚠

renal_impairment

mild renal impairment
caution
FDA Category
N
Dose Adjustment

no specific adjustment needed

Key Recommendations

use with caution; monitor renal function

Monitor

periodic monitoring of renal function

Use with caution and monitor for adverse effects.

⚠

renal_impairment

severe renal impairment
caution
FDA Category
N
Dose Adjustment

reduce dose or increase dosing interval

Key Recommendations

use with caution; consider dose reduction in severe impairment

Monitor

monitor renal function and for signs of accumulation

Use with caution and monitor for adverse effects.

⚠

hepatic_impairment

mild hepatic impairment
caution
FDA Category
N
Dose Adjustment

consider dose reduction

Key Recommendations

use with caution; metabolized in liver

Monitor

monitor liver function and for excessive sedation

Use with caution and monitor for adverse effects.

✗

hepatic_impairment

moderate to severe hepatic impairment
unsafe
FDA Category
N
Dose Adjustment

avoid or use significantly reduced dose

Key Recommendations

avoid use in moderate to severe hepatic impairment due to extensively metabolized in liver

Monitor

monitor liver function closely if use is necessary

Use of this medication in this population requires careful consideration of risks and benefits.

Statistics and clinical data

prescribingFDA
2023

FDA approval year

Value:1959

Original FDA approval date for Carisoprodol

drug_classFDA
2023

Drug class

Value:Skeletal muscle relaxant

Pharmacological classification of Carisoprodol

usageFDA
2023

Primary indication

Value:Acute musculoskeletal pain

Main therapeutic use for muscle pain and spasm

controlled_substanceDEA
2023

DEA Schedule

Value:Schedule IV

Legal classification as controlled substance in the United States

Used to treat acute, painful musculoskeletal conditions including muscle strains, sprains, and other muscle injuries associated with discomfort and pain. It is typically prescribed for short-term relief during the acute phase of these conditions.

The exact mechanism of action is not clearly identified. In animal studies, muscle relaxation induced by carisoprodol has been associated with altered interneuronal activity in the spinal cord and descending reticular formation. It is metabolized in the liver to meprobamate, which may contribute to its effects.

Carisoprodol has potential for abuse, dependence, and withdrawal symptoms, particularly with prolonged use or high doses. Common side effects include drowsiness, dizziness, and headache. It may impair mental and physical abilities required for activities such as driving. Use with alcohol or other CNS depressants should be avoided. Not recommended for use in patients with a history of substance abuse or porphyria.

Contraindications

Conditions and patient states where this medication should be avoided or used with caution.

Do not use (1)

ABSOLUTEhypersensitivity

Known allergy to this medication or its components

Use caution (1)

RELATIVEpregnancy

Consult healthcare provider for benefits vs risks assessment

Official drug label

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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed July 26, 2026. · Read our editorial policy