Clonidine
Catapres (clonidine) is a prescription medication primarily used to treat high blood pressure. It belongs to a class of drugs called alpha-2 adrenergic agonists, which work by relaxing blood vessels and reducing heart rate to improve blood flow. While originally developed for hypertension, it is also prescribed off-label for conditions such as ADHD, anxiety, and certain withdrawal symptoms.
Catapres is a blood pressure medication that relaxes blood vessels and reduces heart rate, with additional uses in managing ADHD and anxiety.
Key facts at a glance
- RxNorm
- 202941
- Generic
- Catapres
- Class
- brand-name
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Catapres is FDA-approved for treating hypertension (high blood pressure) and is often used when other blood pressure medications are not effective or tolerated. Off-label uses include attention deficit hyperactivity disorder (ADHD), anxiety disorders, menopausal hot flashes, and management of withdrawal symptoms from opioids, alcohol, or nicotine.
Catapres stimulates alpha-2 adrenergic receptors in the brain, which reduces the activity of the sympathetic nervous system. This results in decreased heart rate, reduced nerve signals that constrict blood vessels, and overall relaxation of the cardiovascular system, leading to lower blood pressure.
Catapres may cause drowsiness, dry mouth, constipation, or dizziness. Do not stop taking this medication abruptly, as sudden discontinuation can cause a rapid rise in blood pressure (rebound hypertension). Always follow your healthcare provider's instructions for dosing and never adjust your dose without consulting them first.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed July 26, 2026. · Read our editorial policy