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Cefepime

Published: July 26, 2026Updated: July 26, 2026

Cefepime is a fourth-generation cephalosporin antibiotic used to treat serious bacterial infections. It has broad-spectrum activity against both gram-positive and gram-negative bacteria, making it particularly effective for hospital-acquired infections. This medication is typically reserved for moderate to severe infections when other antibiotics may not be sufficient.

Quick summary

Cefepime is a broad-spectrum cephalosporin antibiotic used for serious bacterial infections, especially in hospital settings.

Medically reviewed by WellAlly Editorial TeamLast reviewed July 26, 2026Editorial policy

Key facts at a glance

ATC
J01DE01
RxNorm
20481
Generic
Cefepime
Class
atc-j01
Brands
Exblifep, Zaynich
Availability
rx
Lactation
unknown
Routes
—
Forms
solution, injection
Regions
US, EU, CN, JP
Monitoring
—

This page is for informational purposes only.

Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.

Treats moderate to severe infections including hospital-acquired pneumonia, febrile neutropenia, urinary tract infections, and intra-abdominal infections caused by susceptible bacteria.

As a fourth-generation cephalosporin, it inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins, providing activity against a wide range of gram-positive and gram-negative organisms.

Dose adjustment required in kidney impairment; can cause neurological effects including seizures and confusion; caution advised in penicillin-allergic patients; may result in C. difficile infection; administered intravenously or intramuscularly.

Official drug label

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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed July 26, 2026. · Read our editorial policy