Cefiderocol
Cefiderocol is a novel siderophore cephalosporin antibiotic that works by inhibiting bacterial cell wall synthesis. It is specifically designed to treat complicated urinary tract infections (cUTI) caused by susceptible gram-negative microorganisms, including cases where limited treatment options exist due to antibiotic resistance.
A siderophore cephalosporin antibiotic used for complicated urinary tract infections caused by multidrug-resistant gram-negative bacteria.
Key facts at a glance
- ATC
- J01DI04
- RxNorm
- 2265702
- Generic
- Cefiderocol
- Class
- atc-j01
- Brands
- Fetroja
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- injection
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Treats complicated urinary tract infections (cUTI), including pyelonephritis, in adults with limited or no alternative treatment options due to resistant gram-negative bacteria.
A cephalosporin antibiotic that inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins (PBPs). Its unique siderophore mechanism allows it to actively transport into bacterial cells, particularly effective against gram-negative organisms including multidrug-resistant strains.
Use only when indicated for resistant infections. Cross-reactivity with penicillin allergies is possible. Monitor for C. difficile-associated diarrhea and fungal superinfections. Consult full prescribing information for complete safety details.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed July 26, 2026. · Read our editorial policy