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Cefotaxime Sodium

Published: July 26, 2026Updated: August 25, 2026

Cefotaxime Sodium is a third-generation cephalosporin antibiotic used to treat serious bacterial infections when other antibiotics are ineffective or inappropriate. It is administered intravenously or intramuscularly and is commonly used in hospital settings for severe infections requiring broad-spectrum coverage.

Quick summary

Cefotaxime Sodium is a broad-spectrum cephalosporin antibiotic used to treat serious bacterial infections in hospital settings.

Medically reviewed by WellAlly Editorial TeamLast reviewed August 25, 2026Editorial policy

Key facts at a glance

RxNorm
203117
Generic
Cefotaxime Sodium
Class
pin-variant
Brands
—
Availability
rx
Lactation
unknown
Routes
—
Forms
—
Regions
US, EU, CN, JP
Monitoring
—

This page is for informational purposes only.

Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.

Treatment of serious infections including lower respiratory tract infections, urinary tract infections, intra-abdominal infections, meningitis, bacteremia/sepsis, and post-surgical infections. Particularly useful when gram-negative coverage is needed.

Binds to penicillin-binding proteins (PBPs) and inhibits bacterial cell wall synthesis by blocking transpeptidation, leading to bacterial cell death. Has broad gram-negative and some gram-positive coverage.

Cross-reactivity with penicillin allergies is possible. Monitor renal function during prolonged therapy. May cause GI side effects, rash, or injection site reactions. Use during pregnancy only if clearly needed. Resistance may develop with prolonged use.

Official drug label

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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 25, 2026. · Read our editorial policy