Ceftobiprole Medocaril Sodium
Ceftobiprole medocaril sodium is a fifth-generation cephalosporin antibiotic administered intravenously. It possesses broad-spectrum activity against both Gram-positive and Gram-negative bacteria, including methicillin-resistant Staphylococcus aureus (MRSA). This medication is primarily used to treat serious bacterial infections, particularly hospital-acquired pneumonia and community-acquired pneumonia.
A broad-spectrum IV cephalosporin antibiotic with potent activity against resistant bacteria including MRSA, used for serious pneumonia infections.
Key facts at a glance
- RxNorm
- 2691334
- Generic
- Ceftobiprole Medocaril Sodium
- Class
- pin-variant
- Brands
- Zevtera
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Treatment of hospital-acquired pneumonia (HAP) and community-acquired pneumonia (CAP) caused by susceptible bacteria, including methicillin-resistant Staphylococcus aureus (MRSA) and other drug-resistant organisms. May also be used for skin and soft tissue infections.
As a prodrug, it is converted to its active form, ceftobiprole, which inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins (PBPs). It has particular affinity for PBP2a, allowing it to be effective against MRSA and other resistant Gram-positive bacteria while also covering many Gram-negative pathogens.
Administered via intravenous infusion. Contraindicated in patients with known hypersensitivity to cephalosporins or severe penicillin allergies. Requires monitoring for potential adverse effects including seizures, hypersensitivity reactions, and C. difficile-associated diarrhea. Susceptibility testing is recommended before use to ensure appropriate targeting of susceptible organisms.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 27, 2026. · Read our editorial policy