Dinoprostone Cervical Gel
Cervidil is a prostaglandin E2 vaginal insert used to ripen (soften and dilate) the cervix in pregnant women at term who require labor induction. The medication is placed vaginally and works locally to facilitate the onset of labor when induction is medically necessary.
Cervidil is a vaginal insert containing prostaglandin E2 used to ripen the cervix and induce labor in pregnant women at term.
Key facts at a glance
- RxNorm
- 215960
- Generic
- Cervidil
- Class
- brand-name
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Cervical ripening in pregnant women at term (≥36 weeks) who require labor induction due to medical, obstetric, or fetal indications such as post-term pregnancy, gestational hypertension, diabetes, or intrauterine growth restriction.
Contains dinoprostone (prostaglandin E2), which acts locally on cervical tissue to increase collagenase and elastase activity, promoting collagen breakdown and resulting in cervical softening, effacement, and dilation to facilitate labor.
Must be used in a hospital setting with continuous fetal and uterine monitoring. Contraindicated after previous cesarean section or uterine surgery, with ruptured membranes, or when oxytocin will be used concurrently. Can cause uterine hyperstimulation; should be removed if this occurs. Only one insert should be used per 24-hour period.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed July 26, 2026. · Read our editorial policy