Cetrimide
Cetrimide is a quaternary ammonium compound classified as a topical antiseptic and disinfectant. It is primarily used for skin disinfection, wound cleansing, and preoperative skin preparation. The medication is effective against a broad spectrum of bacteria and some fungi, making it suitable for both medical and veterinary applications.
Cetrimide is a topical antiseptic used for skin disinfection and wound cleansing.
Key facts at a glance
- ATC
- D08AJ04
- RxNorm
- 288088
- Generic
- Cetrimide
- Class
- atc-d08
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- topical
- Forms
- cream, solution
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Dosage and administration
- Usual dose
- 500mg twice daily
- Maximum
- consult physician
- Frequency
- every 12 hours
- Instructions
- Follow physician instructions
- Duration limits
- as prescribed
- Monitoring
- standard
- Usual dose
- 250mg twice daily
- Maximum
- consult physician
- Frequency
- every 12 hours
- Instructions
- Follow physician instructions
- Duration limits
- as prescribed
- Monitoring
- standard
- Usual dose
- 400mg daily
- Maximum
- consult physician
- Frequency
- once daily
- Instructions
- Follow physician instructions
- Duration limits
- as prescribed
- Monitoring
- standard
Overdose information
Special Populations
7 groupspregnancy
first trimesteravoid on large body surface areas
use only on small areas for short durations if benefits outweigh risks
monitor for any skin reactions
Use with caution and monitor for adverse effects.
pregnancy
second third trimesterstandard use
generally considered safe for topical use on intact skin
standard prenatal care
lactation
breastfeedingavoid application to breast or nipple area
do not apply to breast or nipple area before breastfeeding
ensure product is not present on skin before nursing
Use with caution and monitor for adverse effects.
geriatric
elderlystandard use
safe for use on intact skin monitor for skin sensitivity
check for skin irritation especially with repeated use
pediatric_age
infants childrenuse lower concentration and avoid prolonged use
use with caution in neonates and infants under 2 years avoid on large surface areas
monitor for skin irritation and systemic absorption
Use with caution and monitor for adverse effects.
renal_impairment
mild moderatestandard topical use
minimal systemic absorption makes renal impairment less concerning
no specific monitoring required for topical use
hepatic_impairment
any degreestandard topical use
minimal systemic absorption makes hepatic impairment less concerning
no specific monitoring required for topical use
Statistics and clinical data
Drug class
Classification as antiseptic and disinfectant agent
Mechanism of action
Primary pharmacological mechanism
Common uses
Therapeutic applications
Commonly used since
Historical usage information
Cetrimide is used for disinfection of the skin before surgical procedures, cleansing of wounds and burns, preoperative skin preparation, and cleaning of medical equipment. It may also be found in some antiseptic soaps and shampoos for skin and scalp conditions.
As a cationic surfactant and quaternary ammonium compound, Cetrimide disrupts the cell membrane integrity of microorganisms. It is effective against gram-positive bacteria, some gram-negative bacteria, fungi, and certain viruses by causing membrane damage and cell lysis.
For external use only. Avoid contact with eyes, ears, and mucous membranes. May cause skin irritation or hypersensitivity reactions in some individuals. Should not be applied to large areas of burned or extensively damaged skin due to potential systemic absorption. Not for ingestion.
Contraindications
Conditions and patient states where this medication should be avoided or used with caution.
Do not use (1)
Known allergy to this medication or its components
Use caution (1)
Consult healthcare provider for benefits vs risks assessment
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 20, 2026. · Read our editorial policy