Cevimeline Hydrochloride
Cevimeline Hydrochloride is a selective muscarinic receptor agonist used to treat dry mouth (xerostomia) in patients with Sjögren's syndrome by stimulating salivary gland secretion.
Cevimeline is a muscarinic agonist that increases saliva production in Sjögren's syndrome patients.
Key facts at a glance
- RxNorm
- 260036
- Generic
- Cevimeline Hydrochloride
- Class
- pin-variant
- Brands
- Evoxac
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Treatment of dry mouth (xerostomia) associated with Sjögren's syndrome, a chronic autoimmune disorder affecting moisture-producing glands.
Acts as a selective muscarinic M1 and M3 receptor agonist, stimulating secretion from salivary and sweat glands to increase moisture production.
Contraindicated in patients with uncontrolled asthma, narrow-angle glaucoma, or acute iritis. May cause excessive sweating, nausea, rhinitis, or flushing. Use with caution in patients with cardiovascular disease, gallstones, or urinary obstruction. Patients should take doses at regular intervals and avoid exceeding prescribed dosage. Regular monitoring of ocular pressure may be needed in patients with a history of eye conditions.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 27, 2026. · Read our editorial policy