Cevimeline Hydrochloride
Cevimeline Hydrochloride Anhydrous is a selective muscarinic M1 and M3 receptor agonist primarily used to treat dry mouth (xerostomia) in patients with Sjögren's syndrome. It works by stimulating secretion from salivary and lacrimal glands, helping to relieve symptoms of dry mouth and dry eyes. This medication should be used under medical supervision as it may cause cardiovascular, pulmonary, or other adverse effects in susceptible individuals.
A muscarinic agonist used to treat dry mouth in Sjögren's syndrome patients by stimulating salivary gland secretion.
Key facts at a glance
- RxNorm
- 2698548
- Generic
- Cevimeline Hydrochloride Anhydrous
- Class
- pin-variant
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Treatment of xerostomia (dry mouth) in patients with Sjögren's syndrome; may also provide some relief for dry eyes associated with this condition.
Acts as a selective muscarinic M1 and M3 receptor agonist, stimulating cholinergic receptors on salivary and lacrimal glands to increase secretion production.
Use with caution in patients with cardiovascular disease, asthma, COPD, or a history of seizures. May cause sweating, nausea, or rhinitis. Contraindicated in patients with uncontrolled asthma, acute iritis, or narrow-angle glaucoma. Should be avoided in pregnant women unless clearly needed.
Official drug label
WellAlly may earn a referral fee from linked resources at no extra cost to you. Editorial content is never influenced by commercial relationships.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 25, 2026. · Read our editorial policy