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Chlorpheniramine

Published: July 26, 2026Updated: July 26, 2026

Chlor-Trimeton is a brand-name antihistamine containing chlorpheniramine maleate used to relieve allergy symptoms such as sneezing, runny nose, itchy/watery eyes, and itching of the nose or throat. It is also used for symptoms of the common cold. This medication works by blocking histamine, a substance in the body that causes allergic reactions.

Quick summary

Chlor-Trimeton is an antihistamine used to treat allergy and cold symptoms like sneezing, runny nose, and itchy eyes.

Medically reviewed by WellAlly Editorial TeamLast reviewed July 26, 2026Editorial policy

Key facts at a glance

RxNorm
202384
Generic
Chlor-Trimeton
Class
brand-name
Brands
—
Availability
rx
Lactation
unknown
Routes
—
Forms
—
Regions
US, EU, CN, JP
Monitoring
—

This page is for informational purposes only.

Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.

Treatment of allergic conditions including hay fever (seasonal allergies), allergic rhinitis, and common cold symptoms such as sneezing, runny nose, and itchy/watery eyes. May also be used for allergic skin reactions.

Chlorpheniramine is a first-generation H1 antihistamine that works by competitively blocking histamine at H1 receptor sites, thereby reducing allergic symptoms. It also has anticholinergic properties that help dry up respiratory secretions.

Causes drowsiness and sedation; avoid alcohol and operating machinery. Use with caution in elderly patients, those with glaucoma, urinary retention, or thyroid disorders. Not recommended for use just before driving. May interact with other sedatives, MAO inhibitors, and anticholinergic drugs. Consult a doctor before use if pregnant or breastfeeding.

Official drug label

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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed July 26, 2026. · Read our editorial policy