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Chloramphenicol Sodium Succinate

Published: July 26, 2026Updated: August 25, 2026

Chloramphenicol Sodium Succinate is a broad-spectrum antibiotic used primarily for treating serious bacterial infections when other less toxic antibiotics are ineffective or contraindicated. It is administered intravenously and is particularly useful for infections caused by Salmonella, Haemophilus influenzae, and certain meningitis-causing bacteria. Due to potentially serious side effects, it is typically reserved for life-threatening infections in clinical settings.

Quick summary

A potent broad-spectrum antibiotic reserved for serious infections when safer alternatives aren't suitable, known for significant bone marrow toxicity risks.

Medically reviewed by WellAlly Editorial TeamLast reviewed August 25, 2026Editorial policy

Key facts at a glance

RxNorm
47998
Generic
Chloramphenicol Sodium Succinate
Class
pin-variant
Brands
—
Availability
rx
Lactation
unknown
Routes
—
Forms
—
Regions
US, EU, CN, JP
Monitoring
—

This page is for informational purposes only.

Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.

Treats serious bacterial infections including typhoid fever, bacterial meningitis, Rocky Mountain spotted fever, and severe infections caused by Salmonella, Haemophilus influenzae, or anaerobic bacteria when other antibiotics are ineffective or contraindicated.

Binds to the 50S ribosomal subunit of bacteria, inhibiting protein synthesis by preventing peptide bond formation. This bacteriostatic action stops bacterial growth and replication, allowing the immune system to clear the infection.

Requires regular blood monitoring due to risk of dose-dependent and idiosyncratic bone marrow toxicity (including aplastic anemia). Use with extreme caution in neonates (risk of gray baby syndrome). Must be dosed based on weight and renal/hepatic function. Should only be used when clinically indicated due to serious potential adverse effects.

Official drug label

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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 25, 2026. · Read our editorial policy