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Chloramphenicol Succinate

Published: July 26, 2026Updated: August 25, 2026

Chloramphenicol Succinate is a broad-spectrum antibiotic administered intravenously for serious bacterial infections. Due to potentially serious side effects, it is typically reserved for life-threatening infections when other, safer antibiotics are not effective or appropriate. Regular blood monitoring is required during treatment to detect bone marrow toxicity.

Quick summary

A potent broad-spectrum antibiotic reserved for serious infections when safer alternatives aren't suitable.

Medically reviewed by WellAlly Editorial TeamLast reviewed August 25, 2026Editorial policy

Key facts at a glance

RxNorm
20769
Generic
Chloramphenicol Succinate
Class
pin-variant
Brands
—
Availability
rx
Lactation
unknown
Routes
—
Forms
—
Regions
US, EU, CN, JP
Monitoring
—

This page is for informational purposes only.

Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.

Serious systemic infections including bacterial meningitis, rickettsial diseases (such as typhus), and severe salmonella infections. Also used for infections caused by susceptible strains when other antibiotics are contraindicated or ineffective.

Binds to the 50S subunit of bacterial ribosomes, inhibiting protein synthesis by blocking peptidyl transferase activity. This prevents bacterial growth by stopping the formation of essential proteins.

High-risk medication requiring regular complete blood count monitoring due to risk of dose-related bone marrow suppression and rare but potentially fatal aplastic anemia. Should only be used when less toxic alternatives are unavailable. IV form converted to active chloramphenicol in vivo. Use with caution in patients with hepatic impairment.

Official drug label

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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 25, 2026. · Read our editorial policy