Chlorcyclizine Hydrochloride
Chlorcyclizine Hydrochloride is a first-generation antihistamine medication belonging to the piperazine class. It works by blocking histamine H1 receptors, reducing allergic symptoms such as sneezing, itching, and runny nose. This medication is primarily used to treat allergic conditions including hay fever, allergic rhinitis, and urticaria (hives).
An older antihistamine used to relieve allergy symptoms like sneezing, itching, and runny nose by blocking histamine receptors.
Key facts at a glance
- RxNorm
- 235725
- Generic
- Chlorcyclizine Hydrochloride
- Class
- pin-variant
- Brands
- Dallergy Reformulated Nov 2011, Stahist AD, Ahist Antihistamine
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Treats allergic rhinitis, hay fever, seasonal allergies, urticaria (hives), and allergic skin reactions that cause itching or rash.
Blocks histamine H1 receptors in the body, preventing histamine from causing allergic symptoms. It also has mild anticholinergic effects and crosses the blood-brain barrier, which may cause drowsiness.
May cause drowsiness, dry mouth, and blurred vision. Should be used with caution in patients with glaucoma, urinary retention, or enlarged prostate. Avoid alcohol and other sedatives while taking this medication. Not typically recommended for elderly patients due to anticholinergic effects. May interact with other medications; consult a healthcare provider before use.
Official drug label
WellAlly may earn a referral fee from linked resources at no extra cost to you. Editorial content is never influenced by commercial relationships.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 25, 2026. · Read our editorial policy