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Chlormadinone Acetate

Published: July 26, 2026Updated: August 27, 2026

Chlormadinone Acetate is a synthetic progestogen with anti-androgenic properties used primarily as a hormonal contraceptive component and for treating androgen-dependent conditions. It works by suppressing gonadotropin hormones and blocking androgen receptors, making it useful for conditions like benign prostatic hyperplasia, acne, and hirsutism.

Quick summary

Chlormadinone Acetate is a progestogen medication used for contraception and treatment of androgen-related conditions.

Medically reviewed by WellAlly Editorial TeamLast reviewed August 27, 2026Editorial policy

Key facts at a glance

RxNorm
2369
Generic
Chlormadinone Acetate
Class
pin-variant
Brands
—
Availability
rx
Lactation
unknown
Routes
—
Forms
—
Regions
US, EU, CN, JP
Monitoring
—

This page is for informational purposes only.

Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.

Treatment of benign prostatic hyperplasia, androgenic alopecia, acne vulgaris, hirsutism, and used as a progestogen component in combined oral contraceptives. May also be used in hormonal therapy for transgender women.

Acts as a competitive antagonist at androgen receptors, blocking the effects of testosterone and dihydrotestosterone. Also exhibits anti-gonadotropic activity by suppressing luteinizing hormone (LH) and follicle-stimulating hormone (FSH) secretion, reducing androgen production.

Available by prescription only. May cause side effects such as decreased libido, erectile dysfunction, gynecomastia in males, and menstrual irregularities in females. Contraindicated in patients with known or suspected hormone-sensitive malignancies, liver disease, or during pregnancy. Regular monitoring of prostate-specific antigen (PSA) levels recommended during treatment for BPH.

Official drug label

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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 27, 2026. · Read our editorial policy