Chlorobutanol Hemihydrate
Chlorobutanol Hemihydrate is a pharmaceutical preservative and sedative agent commonly used in ophthalmic solutions, injections, and other sterile preparations to prevent microbial growth. It also possesses mild anesthetic and hypnotic properties, making it useful in certain sedative formulations.
A pharmaceutical preservative with antimicrobial and mild sedative properties used in various medical preparations.
Key facts at a glance
- RxNorm
- 1309399
- Generic
- Chlorobutanol Hemihydrate
- Class
- pin-variant
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Used as a preservative in pharmaceutical formulations including ophthalmic solutions, injectables, and topical preparations. Has been employed as a mild sedative and hypnotic agent, and in some cases for its local anesthetic properties.
Exerts antimicrobial activity against bacteria and fungi, helping to maintain sterility of pharmaceutical preparations. Its sedative effects are attributed to central nervous system depression, though the exact mechanism is not fully characterized.
Primarily serves as an excipient/preservative rather than an active therapeutic agent. Should be used within specified concentration limits as directed by pharmaceutical formulations. Use with caution in patients with known sensitivities. Not typically used as a standalone medication for treatment of conditions.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 25, 2026. · Read our editorial policy