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Chloropyramine Hydrochloride

Published: July 26, 2026Updated: August 25, 2026

Chloropyramine Hydrochloride is a first-generation antihistamine medication that blocks H1 histamine receptors to reduce allergic symptoms. It is commonly used to treat various allergic conditions including urticaria, allergic rhinitis, and conjunctivitis.

Quick summary

A first-generation antihistamine used to relieve symptoms of allergic reactions such as hives, runny nose, and itchy eyes.

Medically reviewed by WellAlly Editorial TeamLast reviewed August 25, 2026Editorial policy

Key facts at a glance

RxNorm
236457
Generic
Chloropyramine Hydrochloride
Class
pin-variant
Brands
—
Availability
rx
Lactation
unknown
Routes
—
Forms
—
Regions
US, EU, CN, JP
Monitoring
—

This page is for informational purposes only.

Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.

Treatment of allergic conditions including urticaria (hives), allergic rhinitis, allergic conjunctivitis, atopic dermatitis, and other hypersensitivity reactions. May also be used for anaphylactic reactions as adjunctive therapy.

Blocks H1 histamine receptors, preventing histamine from binding and causing allergic symptoms. As a first-generation antihistamine, it also has anticholinergic and sedative properties.

May cause drowsiness and should be used with caution when driving or operating machinery. Avoid alcohol during treatment. Contraindicated in patients with glaucoma, peptic ulcer, urinary retention, or during acute asthma attacks. Consult a healthcare provider before use during pregnancy or breastfeeding.

Official drug label

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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 25, 2026. · Read our editorial policy