Chloroquine Hydrochloride
Chloroquine Hydrochloride is an antimalarial and anti-inflammatory medication historically used for the treatment and prevention of malaria, as well as certain autoimmune conditions such as rheumatoid arthritis and lupus erythematosus. The medication works by accumulating in the acid compartments of parasites and human cells, though the specific 'pin-variant' classification details are not fully specified.
Antimalarial and anti-inflammatory medication used for malaria treatment and certain autoimmune disorders.
Key facts at a glance
- RxNorm
- 451796
- Generic
- Chloroquine Hydrochloride
- Class
- pin-variant
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Treatment and prevention of malaria caused by Plasmodium species; also used for autoimmune conditions including rheumatoid arthritis, lupus erythematosus, and porphyria cutanea tarda when other therapies are not suitable.
Accumulation in acidic vacuoles of parasites leads to inhibition of hemoglobin degradation and nucleic acid synthesis. May also exert anti-inflammatory effects through immunomodulation, though the specific 'pin-variant' mechanism requires additional context.
Use requires careful monitoring due to risk of retinal toxicity, cardiac effects (QT prolongation), and hematologic changes. Resistance is widespread in certain regions. Contraindicated in patients with retinal disease, porphyria, or known hypersensitivity. Drug interactions with tamoxifen, cyclosporine, and QT-prolonging agents require caution.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 25, 2026. · Read our editorial policy