Chlorzoxazone
Chlorzoxazone is a centrally-acting muscle relaxant used to relieve discomfort caused by acute, painful musculoskeletal conditions such as muscle strains and sprains. It works by acting on the spinal cord and subcortical areas of the brain to reduce muscle spasms and associated pain.
Chlorzoxazone is a prescription muscle relaxant used short-term to treat muscle pain and spasms from injuries.
Key facts at a glance
- ATC
- M03BB03
- RxNorm
- 2410
- Generic
- Chlorzoxazone
- Class
- atc-m03
- Brands
- Lorzone
- Availability
- rx
- Lactation
- unknown
- Routes
- oral
- Forms
- tablet
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Used for the relief of discomfort associated with acute, painful musculoskeletal conditions including muscle strains, sprains, and other muscle injuries. Often prescribed alongside rest, physical therapy, and analgesics for comprehensive treatment.
Acts as a centrally-acting muscle relaxant by depressing reflexes in the spinal cord and subcortical regions of the brain, thereby reducing muscle spasms and pain sensations without directly relaxing skeletal muscle.
Typically prescribed for short-term use (2-3 weeks maximum). May cause drowsiness or dizziness; avoid alcohol and operating machinery until effects are known. Use with caution in patients with liver disease. Common side effects include dizziness, drowsiness, and gastrointestinal upset.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 25, 2026. · Read our editorial policy