Cholic Acid
Cholic acid is a primary bile acid replacement therapy used to treat bile acid synthesis disorders and peroxisomal disorders.
A primary bile acid replacement therapy for bile acid synthesis and peroxisomal disorders.
Key facts at a glance
- ATC
- A05AA03
- RxNorm
- 1440856
- Generic
- Cholic Acid
- Class
- atc-a05
- Brands
- Cholbam
- Availability
- rx
- Lactation
- unknown
- Routes
- oral
- Forms
- capsule
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Treatment of bile acid synthesis disorders due to single enzyme defects in the bile acid biosynthetic pathway, and peroxisomal disorders including Zellweger spectrum disorders, where primary bile acid deficiency occurs.
Cholic acid serves as a replacement for deficient endogenous primary bile acids, restoring normal bile acid pool and feedback inhibition of bile acid synthesis, thereby reducing toxic accumulation of atypical bile acids and cholesterol metabolites.
Treatment should be supervised by specialists experienced in bile acid metabolism disorders. Regular monitoring of liver function and bile acid levels is recommended. Individualize dosing based on clinical response and laboratory parameters.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed July 26, 2026. · Read our editorial policy