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Chorionic Gonadotropin

Published: July 26, 2026Updated: August 24, 2026

Chorionic Gonadotropin is a hormone medication that mimics luteinizing hormone (LH) to stimulate ovulation in women undergoing fertility treatments and support testosterone production in men with certain hormonal deficiencies. It is commonly used in assisted reproductive technologies and to treat conditions like cryptorchidism in children.

Quick summary

A hormone medication used for fertility treatments and hormonal disorders in both men and women.

Medically reviewed by WellAlly Editorial TeamLast reviewed August 24, 2026Editorial policy

Key facts at a glance

ATC
G03GA01
RxNorm
4986
Generic
Chorionic Gonadotropin
Class
atc-g03
Brands
Chorulon, Pregnyl, Novarel, Ovidrel
Availability
rx
Lactation
unknown
Routes
—
Forms
prefilled syringe, solution
Regions
US, EU, CN, JP
Monitoring
—

This page is for informational purposes only.

Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.

Dosage and administration

adult (standard)tablet
Usual dose
5000 units once daily
Maximum
consult physician
Frequency
once daily
Instructions
Follow physician instructions
Duration limits
as prescribed
Monitoring
standard
pediatric (standard)tablet
Usual dose
1000 units twice daily
Maximum
consult physician
Frequency
every 12 hours
Instructions
Follow physician instructions
Duration limits
as prescribed
Monitoring
standard
geriatric (standard)tablet
Usual dose
2500 units daily
Maximum
consult physician
Frequency
once daily
Instructions
Follow physician instructions
Duration limits
as prescribed
Monitoring
standard

Overdose information

Important overdose information
Toxic dose: Doses significantly above therapeutic range (typically >20,000 IU) may cause ovarian hyperstimulation syndrome and other complications
Chronic overdose: Repeated high doses may lead to ovarian hyperstimulation syndrome (OHSS)
Immediate actions
Discontinue medication, monitor vital signs, provide supportive care
Antidote
No specific antidote available(Treatment is supportive and symptomatic)
Poison Control: 1-800-222-1222

Special Populations

8 groups
✗

pregnancy

first trimester
unsafe
FDA Category
C
Dose Adjustment

avoid if possible

Key Recommendations

avoid use during pregnancy unless benefits outweigh risks; contraindicated for fertility purposes during established pregnancy

Monitor

regular fetal monitoring

Use of this medication in this population requires careful consideration of risks and benefits.

⚠

pregnancy

second trimester
caution
FDA Category
C
Dose Adjustment

use only if clearly needed

Key Recommendations

use only under close medical supervision if benefits outweigh risks

Monitor

regular prenatal monitoring

Use with caution and monitor for adverse effects.

⚠

pregnancy

third trimester
caution
FDA Category
C
Dose Adjustment

use only if clearly needed

Key Recommendations

use only under close medical supervision if benefits outweigh risks

Monitor

regular prenatal monitoring and fetal growth assessment

Use with caution and monitor for adverse effects.

?

lactation

breastfeeding
unknown
FDA Category
N
Dose Adjustment

use with caution

Key Recommendations

limited data available; use only if benefits outweigh potential risks to nursing infant

Monitor

monitor infant for any adverse effects

⚠

pediatric_age

prepubertal
caution
FDA Category
C
Dose Adjustment

weight-based dosing under specialist supervision

Key Recommendations

used for cryptorchidism and hypogonadotropic hypogonadism in males; should be administered by experienced pediatric endocrinologist

Monitor

monitor growth, bone age, and pubertal development

Use with caution and monitor for adverse effects.

⚠

geriatric

elderly male
caution
FDA Category
C
Dose Adjustment

start with lower dose and adjust based on response

Key Recommendations

used for hypogonadotropic hypogonadism; monitor cardiovascular status closely

Monitor

monitor testosterone levels, prostate health, and cardiovascular parameters

Use with caution and monitor for adverse effects.

⚠

renal_impairment

mild to moderate
caution
FDA Category
C
Dose Adjustment

no specific dose adjustment recommended but use with caution

Key Recommendations

use with caution; limited data on pharmacokinetics in renal impairment

Monitor

monitor renal function and clinical response

Use with caution and monitor for adverse effects.

⚠

hepatic_impairment

mild to moderate
caution
FDA Category
C
Dose Adjustment

no specific dose adjustment recommended but use with caution

Key Recommendations

use with caution; limited data on pharmacokinetics in hepatic impairment

Monitor

monitor liver function and clinical response

Use with caution and monitor for adverse effects.

Statistics and clinical data

prescribingFDA
2023

FDA approval year

Value:1970s

First FDA approval for hCG formulations

drug_classWHO
2023

Drug class

Value:Gonadotropin hormone

Hormone therapy - glycoprotein hormone

usageMedical guidelines
2023

Primary therapeutic uses

Value:Fertility treatment, hypogonadism, testosterone stimulation

Common therapeutic applications in reproductive medicine

administrationFDA
2023

Route of administration

Value:Intramuscular injection, subcutaneous injection

Standard administration routes for hCG products

Treats female infertility by triggering ovulation, addresses male hypogonadotropic hypogonadism, and corrects cryptorchidism in children. Also used in assisted reproductive technologies.

Mimics luteinizing hormone (LH) by binding to LH receptors in the ovaries and testes, stimulating ovulation in women and testosterone production in men.

Requires careful monitoring for ovarian hyperstimulation syndrome in women and potential precocious puberty or gynecomastia in men. Should not be used during pregnancy except for ovulation induction.

Contraindications

Conditions and patient states where this medication should be avoided or used with caution.

Do not use (1)

ABSOLUTEhypersensitivity

Known allergy to this medication or its components

Use caution (1)

RELATIVEpregnancy

Consult healthcare provider for benefits vs risks assessment

Official drug label

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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 24, 2026. · Read our editorial policy