Cicletanine Hydrochloride
Cicletanine Hydrochloride is an antihypertensive medication used to treat high blood pressure. It belongs to the potassium channel activator class of vasodilators and works by relaxing blood vessels to improve blood flow. This medication is typically prescribed when other blood pressure medications are not effective or tolerated.
Cicletanine Hydrochloride is a vasodilator medication used to treat high blood pressure by opening potassium channels in blood vessels.
Key facts at a glance
- RxNorm
- 235874
- Generic
- Cicletanine Hydrochloride
- Class
- pin-variant
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Cicletanine Hydrochloride is primarily used for the treatment of essential hypertension (high blood pressure without an identifiable cause). It may be used as monotherapy or in combination with other antihypertensive agents when single-agent therapy is insufficient.
As a potassium channel activator, cicletanine opens ATP-sensitive potassium channels in vascular smooth muscle cells. This causes potassium efflux, leading to cell membrane hyperpolarization, which results in smooth muscle relaxation and vasodilation. The vasodilation reduces peripheral vascular resistance and lowers blood pressure.
Common side effects may include headache, flushing, dizziness, and tachycardia due to vasodilation. Fluid retention may occur, sometimes requiring concomitant diuretic use. This medication is contraindicated in patients with certain cardiac conditions and should be used with caution in those with renal impairment. Regular blood pressure monitoring is essential during treatment.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 25, 2026. · Read our editorial policy