Cidofovir
Cidofovir is an antiviral medication used to treat cytomegalovirus (CMV) retinitis, a serious eye infection that can lead to vision loss in immunocompromised patients, particularly those with AIDS. It works by inhibiting viral DNA synthesis to prevent the virus from replicating.
Antiviral agent for treating CMV retinitis in immunocompromised patients.
Key facts at a glance
- RxNorm
- 1546007
- Generic
- Cidofovir Anhydrous
- Class
- pin-variant
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Cidofovir is indicated for the treatment of CMV retinitis in patients with AIDS. It may also be considered for other serious herpesvirus infections in immunocompromised patients when conventional therapies are ineffective or contraindicated.
As a nucleotide analog, cidofovir is phosphorylated intracellularly to its active form, which then inhibits viral DNA polymerase. This blocks viral DNA synthesis and replication of CMV and other herpesviruses.
Cidofovir has significant nephrotoxic potential and requires regular monitoring of renal function. Concomitant probenecid and IV hydration are typically administered to reduce kidney toxicity risk. It is contraindicated in patients with pre-existing renal impairment.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 25, 2026. · Read our editorial policy