Citicoline
Citicoline is a naturally occurring compound that acts as a neuroprotective agent and cognitive enhancer. It is primarily used in the treatment of stroke, traumatic brain injury, and age-related cognitive decline. The medication supports neuronal health by promoting the synthesis of phospholipids in cell membranes and helping to maintain proper neurotransmitter function.
Citicoline is a nootropic medication used to support brain function, protect neurons after stroke or injury, and improve cognitive decline.
Key facts at a glance
- ATC
- N06BX06
- RxNorm
- 997602
- Generic
- Citicoline
- Class
- atc-n06
- Brands
- CerAxon
- Availability
- rx
- Lactation
- unknown
- Routes
- oral
- Forms
- tablet, solution, capsule
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Citicoline is indicated for acute ischemic stroke (to support neurological recovery), chronic cerebrovascular disease, cognitive impairment associated with vascular dementia, traumatic brain injury, and age-related memory decline. It may also be used as adjunct therapy in Parkinson's disease and for certain eye conditions like glaucoma and amblyopia.
Citicoline acts as a precursor to acetylcholine synthesis and supports the formation of phosphatidylcholine, a key component of neuronal cell membranes. It helps reduce glutamate-induced excitotoxicity, supports cellular energy metabolism, and may enhance dopamine levels in the brain.
Citicoline is generally well-tolerated with mild side effects including headache, insomnia, digestive upset, and temporary blood pressure changes. It should not be used in individuals with hypertonia (excessive muscle tone). Pregnant or breastfeeding women should use only if clearly needed. May interact with other medications affecting the central nervous system.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 25, 2026. · Read our editorial policy