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Citric Acid

Published: July 26, 2026Updated: August 25, 2026

Citric Acid, Anhydrous is a crystalline organic acid commonly used as an excipient (inactive ingredient) in pharmaceutical formulations to adjust pH and enhance stability. It is also available as a dietary supplement and is widely found in food and beverage products as an acidulant and preservative.

Quick summary

Citric Acid, Anhydrous is a weak organic acid used primarily as an excipient in medications and supplements rather than as a primary therapeutic agent.

Medically reviewed by WellAlly Editorial TeamLast reviewed August 25, 2026Editorial policy

Key facts at a glance

RxNorm
221946
Generic
Citric Acid, Anhydrous
Class
pin-variant
Brands
—
Availability
rx
Lactation
unknown
Routes
—
Forms
—
Regions
US, EU, CN, JP
Monitoring
—

This page is for informational purposes only.

Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.

Not typically used as a primary medication for treating conditions. As a dietary supplement, it may be used by individuals seeking additional dietary acid intake. In pharmaceutical manufacturing, it serves as a buffering agent and flavoring component in various oral and injectable preparations.

Functions primarily as an acidulant to maintain optimal pH levels in pharmaceutical formulations. Acts as an antioxidant synergist and chelating agent, helping to preserve the stability and efficacy of active ingredients in medications and supplements.

Generally Recognized as Safe (GRAS) by FDA for food and pharmaceutical use. May affect dental enamel with excessive exposure. Can cause gastrointestinal discomfort in some individuals when consumed in large amounts. Always consult a healthcare provider before using as a supplement, especially if taking other medications or having kidney conditions.

Official drug label

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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 25, 2026. · Read our editorial policy