Desloratadine and Pseudoephedrine
Clarinex-D is a prescription combination medication that contains an antihistamine (desloratadine) and a nasal decongestant (pseudoephedrine). It is used to treat symptoms of seasonal allergies, including sneezing, runny nose, itchy/watery eyes, and nasal congestion.
Clarinex-D is an antihistamine-decongestant combination used to relieve seasonal allergy symptoms including nasal congestion.
Key facts at a glance
- RxNorm
- 579752
- Generic
- Clarinex-D
- Class
- brand-name
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Treatment of seasonal allergic rhinitis (hay fever) symptoms including sneezing, runny nose, itchy nose/throat, watery eyes, and nasal congestion.
Desloratadine blocks histamine H1 receptors to reduce allergic symptoms, while pseudoephedrine constricts blood vessels in nasal passages to relieve congestion.
Should not be used by patients with narrow-angle glaucoma, severe hypertension, or urinary retention. May cause insomnia, dry mouth, or increased blood pressure. Consult your healthcare provider before use, especially if you have thyroid disorders, diabetes, or heart conditions.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed July 26, 2026. · Read our editorial policy