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Loratadine and Pseudoephedrine

Published: July 26, 2026Updated: July 26, 2026

Claritin-D is a combination medication that contains an antihistamine (loratadine) and a decongestant (pseudoephedrine). It is primarily used to provide relief from nasal congestion, sneezing, runny nose, and other allergy symptoms in adults and children. This medication is available over-the-counter and requires a pharmacist consultation in many regions due to the decongestant component.

Quick summary

Claritin-D is an antihistamine-decongestant combination that relieves allergy symptoms including nasal congestion, sneezing, and runny nose.

Medically reviewed by WellAlly Editorial TeamLast reviewed July 26, 2026Editorial policy

Key facts at a glance

RxNorm
216076
Generic
Claritin-D
Class
brand-name
Brands
—
Availability
rx
Lactation
unknown
Routes
—
Forms
—
Regions
US, EU, CN, JP
Monitoring
—

This page is for informational purposes only.

Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.

Claritin-D is used to treat seasonal allergies (hay fever), perennial allergies, and nasal congestion. It provides relief from symptoms such as sneezing, runny nose, itchy/watery eyes, and sinus pressure.

Loratadine blocks histamine H1 receptors to reduce allergic reactions, while pseudoephedrine constricts blood vessels in the nasal passages to decrease swelling and congestion. Together, they address both the histamine response and nasal stuffiness.

This medication may not be suitable for individuals with certain conditions including high blood pressure, heart disease, thyroid disorders, diabetes, or prostate issues. Pseudoephedrine may cause insomnia, nervousness, or increased heart rate. Patients should consult a healthcare provider before use if pregnant, breastfeeding, or taking other medications.

Official drug label

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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed July 26, 2026. · Read our editorial policy