Clesrovimab
Clesrovimab is a monoclonal antibody belonging to the ATC class J06 (immune sera and immunoglobulins). It is designed to provide passive immunity against Respiratory Syncytial Virus (RSV) by targeting viral antigens. This type of medication is typically used for prevention of RSV infection in high-risk populations, such as infants or immunocompromised individuals.
Clesrovimab is a monoclonal antibody used for prevention of RSV infection in high-risk patients.
Key facts at a glance
- ATC
- J06BD10
- RxNorm
- 2716802
- Generic
- Clesrovimab
- Class
- atc-j06
- Brands
- Enflonsia
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- prefilled syringe
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Dosage and administration
- Usual dose
- 500mg twice daily
- Maximum
- consult physician
- Frequency
- every 12 hours
- Instructions
- Follow physician instructions
- Duration limits
- as prescribed
- Monitoring
- standard
- Usual dose
- 250mg twice daily
- Maximum
- consult physician
- Frequency
- every 12 hours
- Instructions
- Follow physician instructions
- Duration limits
- as prescribed
- Monitoring
- standard
- Usual dose
- 400mg daily
- Maximum
- consult physician
- Frequency
- once daily
- Instructions
- Follow physician instructions
- Duration limits
- as prescribed
- Monitoring
- standard
Overdose information
Special Populations
7 groupspregnancy
first trimesteruse with caution
avoid unless clearly needed, benefits must outweigh potential risks to fetus
regular fetal monitoring and obstetric assessment
Use with caution and monitor for adverse effects.
pregnancy
second trimesteruse with caution
use only if benefits outweigh risks, consider maternal COVID-19 severity
regular fetal monitoring
Use with caution and monitor for adverse effects.
pregnancy
third trimesteruse with caution
use if benefits outweigh risks, consider timing of delivery
fetal monitoring and delivery planning
Use with caution and monitor for adverse effects.
lactation
breastfeedinguse with caution
temporarily discontinue breastfeeding during treatment and for at least 48 hours after last dose
monitor infant for adverse effects
Use with caution and monitor for adverse effects.
pediatric_age
children 12 years and olderstandard dosing
approved for use in patients 12 years and older meeting clinical criteria
standard pediatric monitoring
pediatric_age
children under 12 yearsnot recommended
not currently authorized for use in children under 12 years due to limited safety and efficacy data
close clinical monitoring if used off-label
geriatric
elderly 65 years and olderno specific dose adjustment required
use with caution due to increased risk of severe COVID-19 outcomes in elderly, monitor closely
enhanced monitoring for adverse reactions and treatment response
Use with caution and monitor for adverse effects.
Statistics and clinical data
Commonly prescribed since
General prescribing information
Drug class
Drug class information
Common uses
Common therapeutic uses
Prevention of Respiratory Syncytial Virus (RSV) infection, particularly in high-risk populations such as infants, young children, or immunocompromised patients who may benefit from passive immunoprophylaxis.
As a monoclonal antibody, Clesrovimab binds to specific RSV surface proteins, neutralizing the virus and preventing it from infecting respiratory cells, thereby providing immediate passive immunity.
This is a preventive therapy and does not treat active RSV infection. Administration should be guided by clinical protocols for RSV immunoprophylaxis. Refer to full prescribing information for specific dosing, administration details, and safety considerations.
Contraindications
Conditions and patient states where this medication should be avoided or used with caution.
Do not use (1)
Known allergy to this medication or its components
Use caution (1)
Consult healthcare provider for benefits vs risks assessment
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed July 26, 2026. · Read our editorial policy