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Estradiol

Published: July 26, 2026Updated: July 26, 2026

Climara Pro is a transdermal hormone replacement therapy (HRT) patch combining estrogen and progestin. It is prescribed for postmenopausal women to relieve moderate to severe menopausal symptoms such as hot flashes, night sweats, and vaginal dryness. The progestin component helps protect the uterine lining in women with an intact uterus.

Quick summary

Climara Pro is a combined estrogen-progestin patch for postmenopausal women to relieve menopausal symptoms.

Medically reviewed by WellAlly Editorial TeamLast reviewed July 26, 2026Editorial policy

Key facts at a glance

RxNorm
402099
Generic
Climara Pro
Class
brand-name
Brands
—
Availability
rx
Lactation
unknown
Routes
—
Forms
—
Regions
US, EU, CN, JP
Monitoring
—

This page is for informational purposes only.

Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.

Treatment of moderate to severe vasomotor symptoms (hot flashes, night sweats) associated with menopause. May also be used for vulvovaginal atrophy symptoms. The progestin component provides endometrial protection in women with a uterus.

Delivers estradiol (synthetic estrogen) and levonorgestrel (progestin) through the skin into the bloodstream. Replaces declining hormone levels during menopause. The progestin component prevents estrogen-induced endometrial hyperplasia.

Apply patch to lower abdomen once weekly. Rotate application sites. Not for use during pregnancy. Discuss cardiovascular risks, breast cancer risk, and venous thromboembolism with your healthcare provider. Women with a uterus require progestin to reduce endometrial cancer risk.

Official drug label

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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed July 26, 2026. · Read our editorial policy