Clobetasol Propionate
Clobetasol Propionate is a highly potent topical corticosteroid used to treat inflammatory skin conditions like psoriasis, severe eczema, and lichen planus. It works by reducing inflammation, itching, and redness by suppressing local immune responses in the skin. This medication is typically prescribed for short-term use when weaker corticosteroids have not been effective.
Clobetasol Propionate is a high-potency topical corticosteroid spray used to treat inflammatory skin conditions such as psoriasis and severe eczema.
Key facts at a glance
- RxNorm
- 21245
- Generic
- Clobetasol Propionate
- Class
- pin-variant
- Brands
- Temovate, Clodan, Impoyz, Tovet, Impeklo, Byqlovi, Olux, Clobex
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Clobetasol Propionate is used to treat inflammatory and itchy skin conditions that have not responded to milder corticosteroids, including plaque psoriasis, severe atopic dermatitis (eczema), lichen planus, and other dermatological conditions causing significant discomfort.
As a corticosteroid, Clobetasol works by binding to glucocorticoid receptors in skin cells, inhibiting the production of inflammatory substances and suppressing local immune activity. This reduces swelling, redness, itching, and discomfort associated with skin inflammation.
This is a very high-potency corticosteroid intended for short-term use only. Avoid application on the face, groin, or armpits unless specifically directed by a healthcare provider. Prolonged use may cause skin thinning, striae (stretch marks), or systemic absorption. Do not use on broken skin, open wounds, or in children without medical supervision. Use exactly as prescribed; do not discontinue abruptly after extended use.
Official drug label
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 25, 2026. · Read our editorial policy