Clobutinol Hydrochloride
Clobutinol Hydrochloride is a centrally-acting cough suppressant (antitussive) that was used to relieve dry, non-productive coughs. It belongs to a class of non-opioid cough suppressants and was available in some European countries. Due to cardiac safety concerns (including QT prolongation and reports of cardiac arrhythmias), this medication has been withdrawn from the market in multiple countries and is no longer recommended for clinical use.
A non-opioid cough suppressant that has been withdrawn from most markets due to cardiac safety concerns.
Key facts at a glance
- RxNorm
- 235956
- Generic
- Clobutinol Hydrochloride
- Class
- pin-variant
- Brands
- —
- Availability
- rx
- Lactation
- unknown
- Routes
- —
- Forms
- —
- Regions
- US, EU, CN, JP
- Monitoring
- —
This page is for informational purposes only.
Do not use this information to diagnose yourself or to replace a physician's advice. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. If you believe you are experiencing a medical emergency, call your local emergency number immediately.
Used for the symptomatic treatment of dry, irritating coughs (antitussive). No longer recommended due to safety concerns.
Acts centrally on the cough center in the medulla oblongata to suppress the cough reflex. As a non-opioid antitussive, it does not possess significant analgesic or respiratory depressant properties.
This medication has been withdrawn from markets in Germany, Austria, and other countries due to reports of QT prolongation and serious cardiac arrhythmias. Healthcare providers should not prescribe this medication and should advise patients to discontinue use if currently taking it. Patients should consult their physician for alternative antitussive options.
Official drug label
WellAlly may earn a referral fee from linked resources at no extra cost to you. Editorial content is never influenced by commercial relationships.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 27, 2026. · Read our editorial policy